You can reach Bordeaux by car from the north (taking the A10 highway or N10), south (taking the A63 highway), or east (N89 / A89). A beltway ("Rocade", A630) goes around the city.
If possible, avoid driving in rush hours (between 8-10AM and 4-7PM), as the beltway and major roads are usually overcrowded. Parking is limited in the city center. Please check with the hotel/B&B where you can leave your car.